Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human GALT
Swissprot
P07902
Synonyms
Gal 1 P uridylyltransferaseGal-1-P uridylyltransferaseGalactose 1 phosphate uridyl transferaseGalactose 1 phosphate uridylyltransferaseGalactose-1-phosphate uridylyltransferaseGALTGALTUDP glucose hexose 1 phosphate uridylyltransferaseUDP-glucose--
Calculated MW
43 kDa
Gene Accession
NP_000146
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4