GATA binding protein 3 (GATA3) is a member of the GATA family of transcription factors (including six members: GATA-1 to GATA-6). It plays an important role in promoting and guiding cell proliferation, development and differentiation in many tissues and cell types. GATA-3 is widely expressed in the epithelial cells of mammary duct glandular cavity and urinary tract epithelium, but not in myoepithelial cells. The expression of GATA-3 is closely associated with the expression of estrogen receptor-α in breast cancer,and there is evidence that GATA-3 can be used to predict the response to hormone therapy in breast cancer patients, and has also been shown to be a new marker for bladder cancer.
Immunogen Information
Synonyms
GATA 3GATA binding factor 3GATA binding protein 3GATA-binding factor 3Gata3GATA3HDRHDRSMGC2346MGC5199MGC5445Trans acting T cell specific transcription factor GATA 3Trans-acting T-cell-specific transcription factor GATA-3
Applications
Reactivity
Human
Tested Applications
IHC-P
Conjugation
Unconjugated
Storage Instructions
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.