GBA Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD85084A
Western blot analysis of extracts of MCF-7 cells using GBA Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of MCF-7 cells using GBA Polyclonal Antibody at dilution of 1:1000.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
GBA Polyclonal Antibody
Catalog Number
RD85084A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human GBA (NP_000148.2).
Gene ID
2629
Swissprot
P04062
Synonyms
GBAGBA1GCBGLUC
Calculated MW
29 kDa/50 kDa/54 kDa/57 kDa/59 kDa
Observed MW
60 kDa

Applications

Circle
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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