GBA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219899A
Western blot analysis of 231 cell lysate using GBA Polyclonal Antibody at dilution of 1:1350
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using GBA Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using GBA Polyclonal Antibody at dilution of 1:55(×200)
Product Name
GBA Polyclonal Antibody
Catalog Number
RD219899A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human GBA
Swissprot
P04062
Synonyms
Acid beta glucosidaseAcid beta-glucosidaseAlgluceraseBeta glucocerebrosidaseBETA GLUCOSIDASEACIDBeta-glucocerebrosidasebetaGCD glucosyl N acylsphingosine glucohydrolaseD-glucosyl-N-acylsphingosine glucohydrolaseEC 3.2.1.45GBAGba proteinGBA
Calculated MW
60 kDa
Observed MW
Refer to figures
Gene Accession
NP000148
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
Concentration
1.56 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas