This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Synthetic peptide of human GCSAM
Swissprot
Q8N6F7
Synonyms
GCAT2GcetGCET2 germinal center expressed transcript 2GCET2 germinal centre expressed transcript 2GcsamGCSAMGerminal center associated lymphomaGerminal center associated lymphoma proteinGerminal center B cell associated protein 2Germinal center B-
Gene Accession
NP_689998
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4