GDF-8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90739A
Western blot with GDF-8 Polyclonal antibody at dilution of 1:1000.lane 1:Hela whole cell lysate,lane 2:Mouse heart,lane 3:Rat heart,lane 4:Rat skeletal muscle
Product Name
GDF-8 Polyclonal Antibody
Catalog Number
RD90739A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Growth/differentiation factor 8(Mstn,GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer,and interacts with WFIKKN2,leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
Immunogen Information
Immunogen
Recombinant Human GDF-8 Protein expressed by E.coli
Swissprot
O14793
Synonyms
Growth/differentiation factor 8GDF-8MyostatinMSTNGDF8
Calculated MW
4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
Observed MW
20 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas