GEMIN2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76424A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using GEMIN2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using GEMIN2 Polyclonal Antibody at dilution 1:40
Product Name
GEMIN2 Polyclonal Antibody
Catalog Number
RD76424A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Immunogen Information
Immunogen
Synthetic peptide of human GEMIN2
Swissprot
O14893
Synonyms
Component of gems 2Gem (nuclear organelle) associated protein 2Gem associated protein 2GEMI2Gemin-2gemin2SIP 1SIP-1SIP1SIP1 deltaSIP1-deltaSMN interacting protein 1SMN interacting protein 1 deltaSMN-interacting protein 1Survival interacting
Gene Accession
NP_003607.1
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas