The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42 similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
Immunogen Information
Immunogen
Recombinant protein of human GFER
Swissprot
P55789
Synonyms
ALRAugmenter of liver regenerationERV1ERV1 homologErv1 like growth factorFAD-linked sulfhydryl oxidase ALRGFERGrowth factor augmenter of liver regenerationGrowth factor erv1 likeHepatic regenerative stimulation substanceHepatopoietinHepatopoiet
Calculated MW
23 kDa
Gene Accession
BC028348
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4