GFRA1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253255A
Western blot analysis of Rat brain tissue lysate using GFRA1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human brain tissue using GFRA1 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using GFRA1 Polyclonal Antibody at dilution of 1:65(×200)
Product Name
GFRA1 Polyclonal Antibody
Catalog Number
RD253255A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human GFRA1
Swissprot
P56159
Synonyms
GDNF family receptor alpha 1GDNF family receptor alpha-1GDNF RGDNF RAGDNF receptor alphaGDNF receptor alpha-1GDNFR alpha 1GDNFR alphaGDNFRGDNFR-alpha-1GDNFRAGDNFRalphaGFR alpha 1GFR alpha1GFR-alpha-1GFRA 1Gfra1GFRA1GFRalpha1Glial cell l
Calculated MW
51 kDa
Observed MW
Refer to figures
Gene Accession
NP005255
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.92 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas