The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization.
Immunogen Information
Immunogen
Recombinant protein of human GH2
Swissprot
P01242
Synonyms
GH 2GH VGH2GHB2GHLGHVGrowth hormone 2Growth hormone B2Growth hormone varianthGH VhGHVPlacenta specific growth hormonePlacental specific growth hormone
Calculated MW
25 kDa
Gene Accession
BC020760
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4