GKN1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219492A
Western blot analysis of Human stomach tissue lysate using GKN1 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using GKN1 Polyclonal Antibody at dilution of 1:30(×200)
Product Name
GKN1 Polyclonal Antibody
Catalog Number
RD219492A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Gastrokine 1 (GKN1),a stomach-specic protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin,belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach,but is absent from gastric adenocarcinomas,gastro-esophageal adenocarcinoma cell lines,and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.
Immunogen Information
Immunogen
Synthetic peptide of human GKN1
Swissprot
Q9NS71
Synonyms
18 kDa antrum mucosa proteinAMP 18AMP-18AMP18Antrum mucosa protein18-KDBRICD 1BRICD1BRICHOS domain containing 1CA 11CA11CA11 geneCA11 proteinFOVFoveolinGastrokine-1Gastrokine1GKN 1Gkn1GKN1MGC70354Protein CA11UNQ489/PRO1005
Calculated MW
22 kDa
Observed MW
Refer to figures
Gene Accession
NP062563
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas