This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Immunogen Information
Immunogen
Recombinant protein of human GLIPR1
Swissprot
P48060
Synonyms
CRISP 7CRISP7GLI pathogenesis related 1GLI pathogenesis-related 1 (glioma)Glioma pathogenesis related protein 1Glioma pathogenesis-related protein 1GLIP1GliPR 1GLIPRGLIPR1Protein RTVP-1RELATED TO TESTIS SPECIFICVESPIDAND PATHOGENESIS PROTEINS
Gene Accession
BC012510
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4