GLUT1,also known as SLC2A1,is an ubiquitously expressed glucose transporter and responsible for the basal level of glucose uptake in most cell types. Human erythrocytes express the highest level of the GLUT1. Defects in SLC2A1 are the cause of GLUT1 deficiency syndrome type 1 and type 2. High expression of GLUT1 has been reported to be a reliable immunohistochemical marker for juvenile hemangiomas. GLUT1 protein may appear as two or more distinct forms among 43 kDa to 55 kDa due to the different glycosylation state. And the conversion of highly glycosylated form of GLUT1 to less glycosylated form has been reported to correlate to differentiation. (8263524,23302780)
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse GLUT1
Swissprot
P11166,P17809,P11167
Synonyms
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity)CSEDYT17DYT18DYT9EIG12erythrocyte/brainErythrocyte/hepatoma glucose transporterfacilitated glucose transporter member 1Glucose transporter 1Glucose transporter type 1Glu
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:600
Concentration
73 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4