This gene encodes a major glucose transporter in the mammalian blood-brain barrier. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human Glut1
Swissprot
P11166
Synonyms
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity)CSEDYT17DYT18DYT9EIG12erythrocyte/brainErythrocyte/hepatoma glucose transporterfacilitated glucose transporter member 1Glucose transporter 1Glucose transporter type 1Glu
Calculated MW
54 kDa
Observed MW
55 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4