Glucose transporter 3(orGLUT3), also known assolute carrier family 2, facilitated glucose transporter member 3(SLC2A3) is aproteinthat in humans is encoded by theSLC2A3gene. GLUT3facilitatesthe transport ofglucoseacross theplasma membranesof mammalian cells. GLUT3 is most known for its specific expression inneuronsand has originally been designated as the neuronal GLUT. GLUT3 has been studied in other cell types with specific glucose requirements, includingsperm, preimplantationembryos, circulatingwhite blood cellsandcarcinomacell lines. GLUT3 has both a higher affinity for glucose and at least a fivefold greater transport capacity than GLUT1, GLUT2 and GLUT4, which is particularly significant for its role in neuronal glucose transport, where ambient glucose levels are fivefold lower than in serum.
Immunogen Information
Immunogen
Synthetic peptide of human SLC2A3
Swissprot
P11169
Synonyms
brainFLJ90380Glucose transporter type 3Glucose transporter type 3 brainGLUT 3GLUT-3GLUT3GTR3Slc2a3Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3Solute carrier family 2facilitated glucose transporter member 3
Calculated MW
54 kDa
Gene Accession
NP_008862
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4