GMNN Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD83222A
Western blot analysis of extracts of various cell lines using GMNN Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using GMNN Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human liver cancer using GMNN Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver cancer using GMNN Polyclonal Antibody at dilution of 1:100 (40x lens).
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Overview

Circle
Product Name
GMNN Polyclonal Antibody
Catalog Number
RD83222A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human GMNN (NP_056979.1).
Gene ID
51053
Swissprot
O75496
Synonyms
GMNNGemMGORS6geminin
Calculated MW
23 kDa
Observed MW
24 kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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