GNAT1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD219919A
Western blot analysis of Human fetal liver tissue lysate  using GNAT1 Polyclonal Antibody at dilution of 1:250
Western blot analysis of Human fetal liver tissue lysate using GNAT1 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using GNAT1 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using GNAT1 Polyclonal Antibody at dilution of 1:25(×200)
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Overview

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Product Name
GNAT1 Polyclonal Antibody
Catalog Number
RD219919A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.GNAT1 (G Protein Subunit Alpha Transducin 1) is a Protein Coding gene. Diseases associated with GNAT1 include Night Blindness, Congenital Stationary, Autosomal Dominant 3 and Night Blindness, Congenital Stationary, Type 1G. Among its related pathways are Phospholipase-C Pathway and Phototransduction. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNAT2.

Immunogen Information

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Immunogen
Synthetic peptide of human GNAT1
Swissprot
P11488
Synonyms
CSNBAD3GBT1GNAT1GNAT1GNATRguanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1guanine nucleotide binding protein G(T) alpha 1 subunitGuanine nucleotide-binding protein G(t) subunit alpha-1Rod specific transducin
Calculated MW
40 kDa
Observed MW
Refer to figures
Gene Accession
NP000163

Applications

Circle
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.66 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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