GPM6A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77825A
Western Blot analysis of Human fetal brain tissue using GPM6A Polyclonal Antibody at dilution of 1:1050
Immunohistochemistry of paraffin-embedded Human brain using GPM6A Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using GPM6A Polyclonal Antibody at dilution of 1:50
Product Name
GPM6A Polyclonal Antibody
Catalog Number
RD77825A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Immunogen Information
Immunogen
Recombinant protein of human GPM6A
Swissprot
P51674
Synonyms
GPM6AGPM6AM6aNeuronal membrane glycoprotein M6-aNeuronal membrane glycoprotein M6-a
Calculated MW
31 kDa
Gene Accession
BC022508
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas