GPM6A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85272A
Western blot analysis of extracts of U-87MG cells using GPM6A Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse stomach using GPM6A Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using GPM6A Polyclonal Antibody at dilution of 1:100 (40x lens).
Variation
Quantity
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Overview
Product Name
GPM6A Polyclonal Antibody
Catalog Number
RD85272A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Immunogen Information
Immunogen
A synthetic peptide of human GPM6A (NP_005268.1).
Gene ID
2823
Swissprot
P51674
Synonyms
GPM6AGPM6M6A
Calculated MW
29 kDa/30 kDa/31 kDa
Observed MW
31 kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas