GPR124 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76856A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GPR124 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using GPR124 Polyclonal Antibody at dilution 1:40
Product Name
GPR124 Polyclonal Antibody
Catalog Number
RD76856A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Immunogen Information
Immunogen
Synthetic peptide of human GPR124
Swissprot
Q96PE1
Synonyms
DKFZp434C211DKFZp434J0911FLJ14390G protein coupled receptor 124G-protein coupled receptor 124GP124GPR 124Gpr124KIAA1531TEM 5TEM5Tumor endothelial marker 5Tumor endothelial marker 5 precursor
Gene Accession
NP_116166
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas