GPS2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89587A
Western blot analysis of extracts of various cell lines using GPS2 Polyclonal Antibody at 1:3000 dilution.
Immunoprecipitation analysis of 150ug extracts of HeLa cells using 3ug GPS2 Polyclonal Antibody.Western blot was performed from the immunoprecipitate using GPS2 Polyclonal Antibody at a dilution of 1:1000.
Product Name
GPS2 Polyclonal Antibody
Catalog Number
RD89587A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Immunogen Information
Immunogen
A synthetic peptide of mouse GPS2
Gene ID
56310
Synonyms
GPS2AMF-1
Calculated MW
51kDa
Observed MW
55kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IP
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IP 1:20-1:50
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.