The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human GRB7
Swissprot
Q14451
Synonyms
B47Epidermal growth factor receptor GRB 7Epidermal growth factor receptor GRB-7GRB7 adapter proteinGRB7GRB7Growth factor receptor bound protein 7Growth factor receptor-bound protein 7OTTHUMP00000164349OTTHUMP00000164350OTTHUMP00000164351OTTHUMP
Gene Accession
BC006535
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4