GRIA4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD252035A
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using GRIA4 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using GRIA4 Polyclonal Antibody at dilution of 1:60(×200)
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Overview

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Product Name
GRIA4 Polyclonal Antibody
Catalog Number
RD252035A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

Immunogen Information

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Immunogen
Synthetic peptide of human GRIA4
Swissprot
P48058
Synonyms
AMPA 4AMPA selective glutamate receptor 4AMPA-selective glutamate receptor 4AMPA4GluA 4GluA4GluR 4GluR DGluR-4GluR-DGluR4GLUR4CGLURDGlutamate receptor 4Glutamate receptor ionotrophic AMPA 4Glutamate receptor ionotropicGRIA 4Gria4GRIA4
Gene Accession
NP000820

Applications

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Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.8 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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