The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Synthetic peptide of human GRIN1
Swissprot
Q05586
Synonyms
GluN1Glutamate [NMDA] receptor subunit zeta-1Glutamate receptor ionotropic N methyl D aspartate 1Glutamate receptor ionotropicN-methyl-D aspartatesubunit 1glutamate receptor ionotropicNMDA 1Grin1MRD8N methyl D aspartate receptorN methyl D aspar
Gene Accession
NP_000823
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4