N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Immunogen Information
Immunogen
Synthetic peptide of human GRIN2B
Swissprot
Q13224
Synonyms
AW490526EIEE27Glutamate [NMDA] receptor subunit epsilon 2Glutamate [NMDA] receptor subunit epsilon-2Glutamate Receptor Ionotropic N Methyl D Aspartate 2BGlutamate Receptor Ionotropic N Methyl D Aspartate subunit 2BGlutamate receptor ionotropic NMDA2
Calculated MW
166 kDa
Gene Accession
NP_000825
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4