N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse NMDAR2B
Swissprot
Q01097,Q00960
Synonyms
AW490526EIEE27Glutamate [NMDA] receptor subunit epsilon 2Glutamate [NMDA] receptor subunit epsilon-2Glutamate Receptor Ionotropic N Methyl D Aspartate 2BGlutamate Receptor Ionotropic N Methyl D Aspartate subunit 2BGlutamate receptor ionotropic NMDA2
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
170 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4