GRK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78533A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GRK2 Polyclonal Antibody at dilution 1:87
Variation
Quantity
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Overview
Product Name
GRK2 Polyclonal Antibody
Catalog Number
RD78533A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Immunogen Information
Immunogen
Synthetic peptide of human ADRBK1
Swissprot
P25098
Synonyms
ADRBK1Adrenergic beta receptor kinase 1ARBK1BARKBARK1Beta adrenergic receptor kinase 1Beta ARK 1Beta ARK1Beta-adrenergic receptor kinase 1Beta-ARK-1FLJ16718G protein coupled receptor kinase 2G-protein coupled receptor kinase 2GRK2
Gene Accession
NP_001610
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas