GSKIP Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD218894A
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using GSKIP Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using GSKIP Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using GSKIP Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GSKIP Polyclonal Antibody at dilution of 1:55(×200)
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Overview

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Product Name
GSKIP Polyclonal Antibody
Catalog Number
RD218894A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

Immunogen Information

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Immunogen
Fusion protein of human GSKIP
Swissprot
Q9P0R6
Synonyms
C14ORF129Chromosome 14 open reading frame 129GSK3-beta interaction proteinGSK3beta interaction proteinGSKIPGSKIPMGC4945UPF0279
Gene Accession
BC004818

Applications

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Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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