This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant Mouse Gsta1 protein expressed by E.coli
Swissprot
P13745
Synonyms
Glutathione S alkyltransferase A1Glutathione S transferase 2Glutathione S transferase Ha subunit 1GST class-alpha member 1GST epsilonGST HA subunit 1GST-epsilonGST2GSTA1-1GSTA1GTH1HA subunit 1MGC131939
Calculated MW
38kDa
Observed MW
50kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.