Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.
Immunogen Information
Immunogen
Recombinant protein of human GSTA2
Swissprot
P09210
Synonyms
EC 2.5.1.18Glutathione S transferase 2Glutathione S transferase A2Glutathione S-alkyltransferase A2Glutathione S-aralkyltransferase A2Glutathione S-aryltransferase A2Glutathione S-transferase alpha 2Glutathione S-transferase GT41AGlutathione S-tra
Gene Accession
BC002895
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4