Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Immunogen Information
Immunogen
Fusion protein of human H3F3B
Swissprot
P84243
Synonyms
H3 histone family 3AH3 histone family 3BH3 histonefamily 3B (H3.3B)H3.3H3.3AH3.3BH33H3F3H3F3AH3f3bHistone H3.3Histone H3.3QHistone H3.AHistone H3.BMGC87782MGC87783