RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity. Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus to poly(U RNA. Involved in mRNA translation regulation, probably at the initiation step. Seems to play a role in PML-nuclear bodies formation.
Immunogen Information
Immunogen
A synthetic peptide of human HABP4
Gene ID
22927
Swissprot
Q5JVS0
Synonyms
IHABP-4IHABP4Ki-1/57SERBP1LHABP4
Calculated MW
43kDa/45kDa
Observed MW
45kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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