HACE1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76862A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HACE1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using HACE1 Polyclonal Antibody at dilution 1:40
Variation
Quantity
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Overview
Product Name
HACE1 Polyclonal Antibody
Catalog Number
RD76862A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
Immunogen Information
Immunogen
Synthetic peptide of human HACE1
Swissprot
Q8IYU2
Synonyms
E3 ubiquitin-protein ligase HACE1HACE 1HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1KIAA1320
Gene Accession
NP_065822
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas