The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Immunogen Information
Immunogen
Recombinant protein of human HCK
Swissprot
P08631
Synonyms
BmkHck 1HckHCKHemopoietic cell kinaseJTK9p59-HCK/p60-HCKp59Hckp59HCK/p60HCKp61HckTyrosine protein kinase HCKTyrosine-protein kinase HCK
Calculated MW
60 kDa
Gene Accession
BC014435
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4