HCN2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78537A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using HCN2 Polyclonal Antibody at dilution 1:80
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using HCN2 Polyclonal Antibody at dilution 1:80
Product Name
HCN2 Polyclonal Antibody
Catalog Number
RD78537A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Immunogen Information
Immunogen
Synthetic peptide of human HCN2
Swissprot
Q9UL51
Synonyms
BCNG-2BCNG2Brain cyclic nucleotide gated channel 2Brain cyclic nucleotide-gated channel 2HAC1Hcn2HCN2Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Gene Accession
NP_001185
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas