HDAC1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218230A
Western blot analysis of 293T 231 Jurkat and RAW264.7 cell lysates using HDAC1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HDAC1 Polyclonal Antibody at dilution of 1:45(×200)
Product Name
HDAC1 Polyclonal Antibody
Catalog Number
RD218230A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Immunogen Information
Immunogen
Fusion protein of human HDAC1
Swissprot
Q13547
Synonyms
DKFZp686H12203GON 10HD1HDAC 1HDAC1HDAC1Histone deacetylase 1Reduced potassium dependency yeast homolog like 1RPD3RPD3L1
Calculated MW
55 kDa
Observed MW
Refer to figures
Gene Accession
BC000301
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.02 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.