HDAC4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD79961A
Immunohistochemistry of paraffin-embedded Human stomach using HDAC4 Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat brain using HDAC4 Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat brain using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using HDAC4 Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Overview

Circle
Product Name
HDAC4 Polyclonal Antibody
Catalog Number
RD79961A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human HDAC4 (NP_006028.2).
Gene ID
9759
Swissprot
P56524
Synonyms
HDAC4AHO3BDMRHA6116HD4HDAC-4HDAC-AHDACA

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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