HDAC4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90094A
Western blot analysis of extracts of various cell lines using HDAC4 Polyclonal Antibody at 1:1000 dilution.
Product Name
HDAC4 Polyclonal Antibody
Catalog Number
RD90094A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Immunogen Information
Immunogen
Recombinant fusion protein of human HDAC4
Gene ID
9759
Swissprot
P56524
Synonyms
HDAC4AHO3BDMRHA6116HD4HDAC-4HDAC-AHDACA
Calculated MW
78kDa/82kDa/90kDa/95kDa/97kDa
Observed MW
160KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.