HDAC4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267932A
Immunohistochemistry of paraffin-embedded Human breast cancer using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse lung using HDAC4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using HDAC4 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
HDAC4 Polyclonal Antibody
Catalog Number
RD267932A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Immunogen Information
Immunogen
A synthetic peptide of human HDAC4 (NP_006028.2).
Gene ID
9759
Swissprot
P56524
Synonyms
HDAC4AHO3BDMRHA6116HD4HDAC-4HDAC-AHDACA
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.