The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress.
Immunogen Information
Immunogen
Fusion protein of human HEBP2
Swissprot
Q9Y5Z4
Synonyms
C6orf34Chromosome 6 open reading frame 34Hebp2HEBP2Heme binding protein 2Heme-binding protein 2Placental protein 23PP23Protein SOULSOUL