Her-2 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD6637
Immunohistochemistry of paraffinembedded Human breast cancer tissue with Her-2 Monoclonal Antibody(Antigen repaired by EDTA). Location: Cell membrane.
Product Name
Her-2 Monoclonal Antibody
Catalog Number
RD6637
Clonality
Monoclonal
Host
Mouse
Background
HER2 (also known as HER2 / neu, C-erbB2, erbB2 or neu) is a transmembrane receptor tyrosine kinase, which is a carcinogenic gene. Its activation will cause malignant transformation and increase the malignant potential of cells (cell proliferation, invasion, etc.). HER-2 is over expressed in 15-25% of primary breast cancer. HER-2 can also be found in gastrointestinal cancer, gastroesophageal cancer, ovarian cancer, well differentiated endometrial cancer and some salivary duct tumors. HER2-expressed breast cancer is usually associated with estrogen and progesterone receptor negative. Therefore, the poor prognosis is related to the expression of HER2.
Immunogen Information
Swissprot
P04626
Applications
Reactivity
Human
Tested Applications
Ready to use for IHC-P
Concentration
100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Storage Buffer
TBS with 0.1% Proclin300, PH7.4