HERPUD1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD89779A
Western blot analysis of extracts of various cell lines using HERPUD1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using HERPUD1 Polyclonal Antibody at 1:1000 dilution.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
HERPUD1 Polyclonal Antibody
Catalog Number
RD89779A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human HERPUD1
Gene ID
9709
Swissprot
Q15011
Synonyms
HERPUD1HERPMif1SUP
Calculated MW
14kDa
Observed MW
15kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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