The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human HINT1
Swissprot
P49773
Synonyms
Adenosine 5' monophosphoramidaseAdenosine 5''-monophosphoramidaseHINT 1HINT1HINT1Histidine triad nucleotide binding protein 1Histidine triad nucleotide-binding protein 1PKCI 1PKCI-1PKCI1PRKCNH1Protein kinase C inhibitor 1Protein kinase C inter
Calculated MW
14 kDa
Gene Accession
NP_005331
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4