Hint2 (histidine triad nucleotide binding protein 2), also known as HIT-17, is a 163 amino acid secreted protein that contains one HIT domain, a histidine triad that has catalytic activity toward the -phosphate of ribonucleotides. Via its HIT domain, Hint2 is thought to function as a hydrolase that is encoded by a gene whicHuman, Mouseaps to chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Immunogen Information
Immunogen
Recombinant protein of human HINT2
Swissprot
Q9BX68
Synonyms
1190005L05RikHINT-2HINT-3HINT2HINT2histidine triad nucleotide binding protein 2Histidine triad nucleotide-binding protein 2HIT-17HIT-17kDamitochondrialPKCI-1-related HIT proteinProtein kinase C inhibitor 2
Calculated MW
17 kDa
Gene Accession
BC047737
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4