Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Immunogen Information
Immunogen
Synthetic peptide of human HRH3
Swissprot
Q9Y5N1
Synonyms
G protein coupled receptor 97G-protein coupled receptor 97GPCR 97GPCR97H3RHH 3RHH3 RHH3RHistamine H3 receptorHistamine receptor H3HRH 3HRH3HRH3OTTHUMP00000031459
Gene Accession
NP_009163
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4