Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Immunogen Information
Immunogen
Recombinant protein of human HK2
Swissprot
P52789
Synonyms
DKFZp686M1669Hexokinase 2Hexokinase 2 muscleHexokinase type IIHexokinase-2HK 2HK IIHK2HKIIHxK 2HxK2HXK2Muscle form hexokinase
Calculated MW
102 kDa
Gene Accession
BC021116
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:100-1:300
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4