HLA-E Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218997A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HLA-E Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HLA-E Polyclonal Antibody at dilution of 1:50(×200)
Product Name
HLA-E Polyclonal Antibody
Catalog Number
RD218997A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Immunogen Information
Immunogen
Fusion protein of human HLA-E
Swissprot
P13747
Synonyms
HLA class I histocompatibility antigen E alpha chainEA1.2EA2.1HLA 6.2HLA class I histocompatibility antigen alpha chain EHLA class I histocompatibility antigen E alpha chain precursorHLA class I histocompatibility antigen E alpha chain precursorHL
Gene Accession
BC002578
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas