HMGCL Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Mouse thymus and Human ovarian cancer tissue, Mouse heart, Human fetal liver, Mouse liver tissue and SKOV3 cell using HMGCL Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human ovarian cancer using HMGCL Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer using HMGCL Polyclonal Antibody at dilution of 1:30
Product Name
HMGCL Polyclonal Antibody
Catalog Number
RD78151A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human HMGCL
Swissprot
P35914
Synonyms
3 hydroxy 3 methylglutaryl CoA lyase3 hydroxy 3 methylglutaryl Coenzyme A lyase3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase (hydroxymethylglutaricaciduria)3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase3-hydroxy-3-methylglutarate-CoA lyaseHLH
Calculated MW
34 kDa
Gene Accession
BC010570
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas