HNF1A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253258A
Western blot analysis of Human left kidney cancer tissue and HEPG2 cell lysates using HNF1A Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HNF1A Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using HNF1A Polyclonal Antibody at dilution of 1:25(×200)
Product Name
HNF1A Polyclonal Antibody
Catalog Number
RD253258A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Synthetic peptide of human HNF1A
Swissprot
P20823
Synonyms
Albumin proximal factorHepatic nuclear factor 1 alphaHepatic nuclear factor 1Hepatic transcription factor 1 alphaHepatic transcription factor 1Hepatocyte nuclear factor 1-alphaHNF 1HNF 1AHNF-1-alphaHNF-1Ahnf1aHNF1AInterferon production regulat
Calculated MW
67 kDa
Observed MW
Refer to figures
Gene Accession
NP000536
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Concentration
0.66 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas