HNF1B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76431A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using HNF1B Polyclonal Antibody at dilution 1:80
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using HNF1B Polyclonal Antibody at dilution 1:80
Variation
Quantity
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Overview
Product Name
HNF1B Polyclonal Antibody
Catalog Number
RD76431A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human HNF1B
Swissprot
P35680
Synonyms
FJHNHepatocyte nuclear factor 1 betaHepatocyte nuclear factor 1-betaHNF 1BHNF 2HNF-1-betaHNF-1BHNF1 betaHNF1 homeobox BHNF1BHNF1BHNF1betaHNF2Homeoprotein LF B3Homeoprotein LFB3HPC11LF B3LFB3MODY 5MODY5TCF 2TCF 2 proteinTCF-2TCF2TCF
Gene Accession
NP_000449.1
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas